Preserving Life by Emulating Nature
A robust preservation platform for cells, tissues, organs, and regenerative medicines.
We advance regenerative medicine and organ transplantation with a ground-breaking biopreservation platform. We enable safe and reliable organs, engineered tissues, and cell therapies to patients in need and break down the barriers of time and distance.
You have Time.
Inadequate preservation impacts:
Only 10% of patients get an organ in time.
One patient on the waiting list dies every hour.
80% of transplantable organs are not used.
Medical teams only have hours to recover and transplant an organ.
Cryopreservation is a crucial part of manufacturing regenerative medicines.
Existing standards in cryopreservation use 5-10% dimethyl sulfoxide (DMSO) and often serum or serum albumin.
These products have not been significantly improved for over 50 years.
DMSO exhibits acute toxicity in patients and causes adverse cell mutations at low doses (0.1%).
"Look deep into nature, and then you will understand everything better. "
Arctic fish thrive in sub-zero environments because of Antifreeze Proteins (AFPs) that reduce the freezing point of water and bind nucleated ice to control the growth of lethal ice crystals. Inspired by AFPs, we developed a chemically defined antifreeze molecule that is hyper effective, non-toxic, biocompatible, and scalable.
Chemically Defined Safe & Effective Cryopreservation
XT-Thrive® is a DMSO-free, serum-free, protein-free, and chemically defined cryopreservation media for the preservation of mammalian cells at ultra-low temperatures (-70° C to -196° C). It is a non-toxic & hyper-effective alternative to DMSO and serum products. It is plug and play for cell & tissue manufacturing processes.
Organ and Tissue Preservation Solution
XT-ViVo® is a novel subzero preservation solution that will enable safe long-term ice-free storage and transport for tissues and organs. XT-ViVo® has been designated as a Breakthrough Device by the FDA.