Removing Time from the Equation
X-Therma enables the robust preservation of cells, tissues, organs, and other biologics by leveraging our proprietary peptoid. The peptoid inhibits lethal ice crystals, allowing long-term sub-zero storage of biological materials while maintaining unparalleled functionality and viability.

How it Began
When she was 8 years old, Xiaoxi’s beloved grandfather passed away. If he had received a donor liver, he would have had more time to spend with loved ones.
Xiaoxi has since dedicated her life to finding a solution that increases organ availability. In 2014 she obtained her doctorate in medicinal chemistry from SUNY-Buffalo. Soon after, she established X-Therma to bring her vision of eradicating organ waitlists to life.


X-Therma History


2015
Xiaoxi Wei, CEO began her research work for X-Therma at Lawrence Berkeley National Laboratory. She received her first grant awarded to X-Therma. Provisional patent filed.

2016
Only 1 Year later X-Therma had 2 additional grants in implementation and a Team of 4. First successful proof of concept for novel preservation of cell lines.

2017
X-Therma now has 5 grants running simultaneously and filed additional provisional patents.
2018
X-Therma Partnered with Johns Hopkins University and Dr. Gerald Brandacher on several grants. X-Therma awarded first patent claim set!

2019
Successful in vivo mouse heart transplant with Johns Hopkins University.
2020
X-Therma survived the Covid-19 pandemic and was able to continue with successful ex vivo organ transplantations.

2021
X-Therma closed an oversubscribed $13M Series A financing led by LOREA AG. The European office was opened.
2022
The FDA designated X-Therma's proprietary organ preservation solution, XT-ViVo®, and TimeSeal® Organ Transport Device, Breakthrough Device status.


News
From Arctic Fish To New Cell Therapy Preservation Technologies
Cryopreservation should maintain the function and viability of organs and cell therapies, but the process is riddled with challenges. Can nature-inspired proteins make a difference?

Improving Health Equity Through Worldwide Organ Sharing
The organ transplantation field has experienced numerous barriers which have contributed to the creation of organ accessibility issues worldwide. To help tackle these challenges, X-Therma

Taking the Toxins Out of Cell Therapy Storage: A New Cryopreservation Molecule
The preservation of living cells and tissues is an often-underappreciated obstacle in the clinical lab. Cryogenic temperatures attempt to address this challenge by minimizing biochemical