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Organ Preservation

A Bioinspired And Chemically Defined Alternative To Dimethyl Sulfoxide For The Cryopreservation Of Human Hematopoietic Stem Cells

The cryopreservation of hematopoietic cells using dimethyl sulfoxide (DMSO) and serum is a common procedure used in transplantation. However, DMSO has clinical and biological side effects due to its toxicity, and serum introduces variation and safety risks. Explore the development of a novel class of ice-interactive cryoprotectants inspired by natural antifreeze proteins.

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