What is the problem we are solving?
Low temperature extends life, but ice is our enemy. Ice damages stem cells, transplantable organs, and other regenerative medicines as they experience ‘freezer burn’ during biostorage. To date, formulas to prevent ice formation during freezing have remained relatively unchanged over the past 50 years leading to great challenges in successful biostorage.
The leading ice-prevention compound e.g. DMSO is toxic and ineffective and causes cell death after storage. Animal-derived serum is a must-have, but introduces batch-to-batch variation, additional biohazards and raises ethical issues.
Why are we different?
We believe it is time to make changes. We are devoted to developing safe and effective biostorage methods using an ice prevention material that is non-toxic and hyper effective. We use biomimetic nanotechnology, a unique approach that embraces the beauty of Nature’s design and the power of nanotechnology.
Where are we now?
X-Therma is located in the San Francisco Bay Area. We are selected as a User at the Lawrence Berkeley National Laboratory, where we have access to state-of-the-art instruments and facilities for rapid discovery. At X-Therma, we developed a state-of-the-art ice-blocking preservation solution that is DMSO-free, protein-free, serum-free, and chemically defined. Our first-in-class, hyper effective (500x), and non-toxic antifreeze material offers safer transport and long-term Biobanking, that is going to transform the regenerative medicine market by enabling new technologies and therapies. Classified as a class I medical device, X-Therma’s product maintains significant regulatory advantages.
Who is with us?
The market is warm and excited for a new breakthrough. X-Therma has excellent timing to participate in the new grand challenge “Organs on demand” initiated by the US Federal Government through major funding agencies.